Article
Novel insights into the genetic background of genetically modified mice.
Transgenic research - 1 Jun 2018
Dobrowolski Peter, Fischer Melina, Naumann Ronald
Abstract excerpt
Unclear or misclassified genetic background of laboratory rodents or a lack of strain awareness causes a number of difficulties in performing or reproducing scientific experiments. Until now, genetic differentiation between strains and substrains of inbred mice has been a challenge. We have developed a screening method for analyzing inbred strains regarding their genetic background. It is based on 240 highly...
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