Article
Therapeutic targets for endometriosis: Genome-wide Mendelian randomization and colocalization analyses.
Gene - 30 Jan 2024
Zeng Pengfei, Lu Liyue, Zhang Hanxiao, Li Yanting, Tan Shufa, Yu Tong, Zhou Hang
Abstract excerpt
BACKGROUND: Endometriosis (EM) greatly affects women's reproductive health, identifying new drug targets for EM is urgently needed. This study utilizes comprehensive genome-wide Mendelian randomization (MR) and colocalization analyses, using genomic data, to identify potential therapeutic approaches for EM. METHODS: Genome-wide cis-expression quantitative trait loci (cis-eQTL) data were obtained from GTEx V8,...
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