Article
SARS-CoV-2 NSP12 associates with TRiC and the P323L substitution acts as a host adaption.
Journal of virology - 30 Nov 2023
Alruwaili Muhannad, Armstrong Stuart, Prince Tessa, Erdmann Maximillian, Matthews David A, Luu Lisa, Davidson Andrew, Aljabr Waleed, Hiscox Julian A
Abstract excerpt
IMPORTANCE: SARS-CoV-2 has caused a worldwide health and economic crisis. During the course of the pandemic, genetic changes occurred in the virus, which have resulted in new properties of the virus-particularly around gains in transmission and the ability to partially evade either natural or vaccine-acquired immunity. Some of these viruses have been labeled Variants of Concern (VoCs). At the root of all VoCs are...
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