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Article

Genetic polymorphisms in VEGFA and VEGFR2 genes associated with coronary heart disease susceptibility and severity.

Molecular biology reports - 1 Dec 2023

Hajer Foddha, Hana Saoud, Saoussen Chouchene, Abdelhak Foddha, Nadia Bouzidi, Ameni Dhiflaoui, Habib Gamra, Hassen Ben Abdennebi, Amel Haj Khelil

Abstract excerpt

BACKGROUND: Vascular endothelial growth factor A (VEGFA) is well acknowledged as a powerful angiogenesis-promoting agent mainly through its receptor VEGFR2. Ischemia stimulates VEGFA/VEGFR2 signaling pathway and elevated serum levels of VEGFA were detected in coronary heart disease (CHD) patients. The goal of the current study is to determine how four SNPs in the genes for VEGFA (rs3025039 and rs699947) and...

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Identifiers

PMID: 37924452
DOI: 10.1007/s11033-023-08899-z

Genes

VEGFA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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