Article
Association of Genetic Polymorphisms on Vascular Endothelial Growth Factor and its Receptor Genes with Susceptibility to Coronary Heart Disease.
Medical science monitor : international medical journal of experimental and clinical research - 4 Jan 2016
Li Lei, Pan Yongquan, Dai Li, Liu Bing, Zhang Dongming
Abstract excerpt
BACKGROUND: Coronary heart disease (CHD) is a cardiovascular disease characterized by high morbidity and mortality. Vascular endothelial growth factor (VEGF) and its receptor, named kinase insert domain-containing receptor (KDR, or VEGFR2), which are involved with angiogenesis and vascular repair, could partly contribute to the development of CHD. The aim of this study, therefore, was to investigate the potential...
Topics
- Aged
- Case-Control Studies
- Coronary Disease
- Female
- Genetic Predisposition to Disease
- Genotype
- Haplotypes
- Healthy Volunteers
- Humans
- Male
- Middle Aged