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Article

Association of VEGFA Gene Polymorphisms with the Susceptibility of Coronary Heart Disease in the Chinese Han Population.

Cardiovascular toxicology - 1 Jul 2025

Huang Kang, Lu Shijuan, Zhou Yilei, Lin Dehong, Chen Zibin, Zhong Zanrui, Zhong Jianghua

Abstract excerpt

Coronary heart disease (CHD) is a prevalent cardiovascular' condition characterized by high morbidity and mortality rates, with a significant genetic component. The VEGFA gene plays a crucial role in the development of CHD. This study aims to evaluate the influence of VEGFA gene polymorphisms on CHD susceptibility. Peripheral blood samples were collected from 479 CHD patients and 479 healthy controls. We...

Read the complete abstract on PubMed

Topics

Adult
Aged
Female
Humans
Male
Middle Aged
Case-Control Studies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

China

Coronary Disease

Gene Frequency

Genetic Association Studies

Genetic Predisposition to Disease

Odds Ratio

Phenotype

Polymorphism, Single Nucleotide

Risk Assessment

Risk Factors

Vascular Endothelial Growth Factor A

Source

Identifiers

PMID: 40445573
DOI: 10.1007/s12012-025-10003-9

Genes

VEGFA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 22 Oct 2026.

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Association of VEGFA Gene Polymorphisms with the Susceptibility of Coronary Heart Disease in the Chinese Han Population.PMID 40445573Read ↗

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