Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Innovative technology for evaluation of sperm DNA double-strand breaks diagnoses male factor infertility and prevents reproductive failures

3 Nov 2023

Abstract excerpt

Neutral comet assay has been available for two decades to evaluate sperm double-strand breaks (DSBs). However, its clinical usability is limited due to its complex and time-consuming procedure, as well as the lack of a standardized scoring system. The aim of this study was to: develop a rapid diagnostic method for DSBs, Sperm DNA Fragmentation Releasing Assay (SDFR), and explore the association between DSBs and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Prenatal Screening and Diagnostics
Share to Reproductive Biology and Fertility
Share to Sperm and Testicular Function

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37923811
DOI: 10.1038/s41598-023-46049-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Innovative technology for evaluation of sperm DNA double-strand breaks diagnoses male factor infertility and prevents reproductive failuresPMID 37923811Read ↗

Using the alkaline comet assay in prognostic tests for male infertility and assisted reproductive technology outcomesSemantic proximity Read ↗

What should be done for men with sperm DNA fragmentation?Semantic proximity Read ↗

The Impact of Single- and Double-Strand DNA Breaks in Human Spermatozoa on Assisted ReproductionSemantic proximity Read ↗

Sperm DNA damage output parameters measured by the alkaline Comet assay and their importanceSemantic proximity Read ↗

Sperm DNA fragmentation test: usefulness in assessing male fertility and assisted reproductive technology outcomesSemantic proximity Read ↗

Sperm DNA Fragmentation: causes, evaluation and management in male infertilitySemantic proximity Read ↗

Sperm DNA Fragmentation in Reproductive MedicineSemantic proximity Read ↗

Comprehensive analysis of sperm DNA fragmentation by five different assays: TUNEL assay, SCSA, SCD test and alkaline and neutral Comet assaySemantic proximity Read ↗

Sperm DNA damage and its impact on male reproductive health: a critical review for clinicians, reproductive professionals and researchersSemantic proximity Read ↗

Comparative analysis of tests used to assess sperm chromatin integrity and DNA fragmentationSemantic proximity Read ↗

Sperm DNA Fragmentation: A New Guideline for CliniciansSemantic proximity Read ↗

Clinical utility of sperm DNA fragmentation testing: concise practice recommendationsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.