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Sperm DNA Fragmentation: A New Guideline for Clinicians

1 Jan 2020

Abstract excerpt

Sperm DNA integrity is crucial for fertilization and development of healthy offspring. The spermatozoon undergoes extensive molecular remodeling of its nucleus during later phases of spermatogenesis, which imparts compaction and protects the genetic content. Testicular (defective maturation and abortive apoptosis) and post-testicular (oxidative stress) mechanisms are implicated in the etiology of sperm DNA...

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PMID: 32777871
DOI: 10.5534/wjmh.200128

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