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Using the alkaline comet assay in prognostic tests for male infertility and assisted reproductive technology outcomes

17 Feb 2008

Abstract excerpt

Infertility affects one in six couples in Europe during their reproductive years with dysfunctional sperm being one of the most common causes. Conventional semen analysis has proven variable and lacking in prognostic value so, over the past decade, more useful molecular fertility biomarkers have been explored. Among the tests showing most promise are those measuring sperm DNA quality. Sperm DNA damage has been...

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PMID: 18325925
DOI: 10.1093/mutage/gem052

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