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Sperm DNA Fragmentation in Reproductive Medicine

1 Jul 2022

Abstract excerpt

Approximately 15% of the world's couples suffer from infertility during their reproductive period of which the male factor is responsible for 50% of cases. Male factor infertility is multifactorial in origin, and sperm DNA fragmentation (SDF) has also been linked to male infertility including idiopathic male infertility. Some degree of controlled DNA nicking is essential for adequate DNA compaction, but excessive...

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PMID: 36341018
DOI: 10.4103/jhrs.jhrs_82_22

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