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Neuronal TIMP2 regulates hippocampus-dependent plasticity and extracellular matrix complexity

1 Sept 2023

Abstract excerpt

Functional output of the hippocampus, a brain region subserving memory function, depends on highly orchestrated cellular and molecular processes that regulate synaptic plasticity throughout life. The structural requirements of such plasticity and molecular events involved in this regulation are poorly understood. Specific molecules, including tissue inhibitor of metalloproteinases-2 (TIMP2) have been implicated...

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PMID: 37914840
DOI: 10.1038/s41380-023-02296-5

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