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Article

Natural, Persistent Oscillations in a Spatial Multi-Strain Disease System with Application to Dengue

24 Oct 2013

Abstract excerpt

Many infectious diseases are not maintained in a state of equilibrium but exhibit significant fluctuations in prevalence over time. For pathogens that consist of multiple antigenic types or strains, such as influenza, malaria or dengue, these fluctuations often take on the form of regular or irregular epidemic outbreaks in addition to oscillatory prevalence levels of the constituent strains. To explain the...

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PMID: 24204241
DOI: 10.1371/journal.pcbi.1003308

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