Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Loss of the methylarginine reader function of SND1 confers resistance to hepatocellular carcinoma.

The Biochemical journal - 29 Nov 2023

Wright Tanner, Wang Yalong, Stratton Sabrina A, Sebastian Manu, Liu Bin, Johnson David G, Bedford Mark T

Abstract excerpt

Staphylococcal nuclease Tudor domain containing 1 (SND1) protein is an oncogene that 'reads' methylarginine marks through its Tudor domain. Specifically, it recognizes methylation marks deposited by protein arginine methyltransferase 5 (PRMT5), which is also known to promote tumorigenesis. Although SND1 can drive hepatocellular carcinoma (HCC), it is unclear whether the SND1 Tudor domain is needed to promote HCC....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Hepatocellular
Share to Endonucleases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Liver Neoplasms

Share to Nuclear Proteins

Share to Transcription Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 37905668
DOI: 10.1042/BCJ20230384
PMCID: PMC10860161

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Loss of the methylarginine reader function of SND1 confers resistance to hepatocellular carcinoma.PMID 37905668Read ↗

Role of the staphylococcal nuclease and tudor domain containing 1 in oncogenesis (Review)Semantic proximity Read ↗

Structural basis for recognition of arginine methylated Piwi proteins by the extended Tudor domainSemantic proximity Read ↗

Insights Into SND1 Oncogene Promoter RegulationSemantic proximity Read ↗

KDM6A-SND1 interaction maintains genomic stability by protecting the nascent DNA and contributes to cancer chemoresistance.Semantic proximity Read ↗

SND1, a Component of RNA-Induced Silencing Complex, Is Up-regulated in Human Colon Cancers and Implicated in Early Stage Colon CarcinogenesisSemantic proximity Read ↗

MTDH-SND1 interaction is crucial for expansion and activity of tumor-initiating cells in diverse oncogene- and carcinogen-induced mammary tumors.Semantic proximity Read ↗

Suppression of SAMSN1 Expression is Associated with the Malignant Phenotype of Hepatocellular Carcinoma.Semantic proximity Read ↗

Identification of rtl1, a retrotransposon-derived imprinted gene, as a novel driver of hepatocarcinogenesis.Semantic proximity Read ↗

Hepatocarcinogenesis Driven by GSNOR Deficiency Is Prevented by iNOS InhibitionSemantic proximity Read ↗

Attenuated RND1 Expression Confers Malignant Phenotype and Predicts Poor Prognosis in Hepatocellular Carcinoma.Semantic proximity Read ↗

Structural and functional insights into human Tudor-SN, a key component linking RNA interference and editingSemantic proximity Read ↗

NFκB1 is a suppressor of neutrophil-driven hepatocellular carcinoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.