Article
Suppression of SAMSN1 Expression is Associated with the Malignant Phenotype of Hepatocellular Carcinoma.
Annals of surgical oncology - 1 Dec 2015
Sueoka Satoshi, Kanda Mitsuro, Sugimoto Hiroyuki, Shimizu Dai, Nomoto Shuji, Oya Hisaharu, Takami Hideki, Ezaka Kazuhiro, Hashimoto Ryoji, Tanaka Yuri, Okamura Yukiyasu, Yamada Suguru, Fujii Tsutomu, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro
Abstract excerpt
BACKGROUND: Identification of molecular markers for sensitive detection of hepatocellular carcinoma (HCC) is required to achieve efficacious personalized therapy. METHODS: We focused here on SAM domain, SH3 domain, and nuclear localization signals 1 (SAMSN1) and investigated expression and methylation status of SAMSN1 in HCC cell lines and 144 pairs of surgical specimens. RESULTS: SAMSN1 was expressed at...
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