Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Relationship between COVID-19 Severity in Children and Immunoregulatory Gene Polymorphism.

Viruses - 14 Oct 2023

Kozak Kateryna, Pavlyshyn Halyna, Kamyshnyi Oleksandr, Shevchuk Oksana, Korda Mykhaylo, Vari Sandor G

Abstract excerpt

Coronavirus disease (COVID-19) and its outcomes remain one of the most challenging problems today. COVID-19 in children could be asymptomatic, but can result in a fatal outcome; therefore, predictions of the disease severity are important. The goal was to investigate the human genetic factors that could be associated with COVID-19 severity in children. Single-nucleotide polymorphisms of the following genes were...

Topics

Male
Child
Case-Control Studies
SARS-CoV-2
Coronavirus
Angiotensin-Converting Enzyme 2
Patient Acuity
Polymorphism, Single Nucleotide
Caspase 3
Humans
COVID-19

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Systemic Inflammatory Response Syndrome

Source

Open in PubMed Open full text

Identifiers

PMID: 37896870
DOI: 10.3390/v15102093
PMCID: PMC10612096

Genes

ACE2
CASP3
CD40
IFNAR2
OAS1
FCGR2A
OAS3
TYK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-37896870-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Relationship between COVID-19 Severity in Children and Immunoregulatory Gene Polymorphism.PMID 37896870Read ↗

Genes Polymorphisms and Their Association with COVID-19 Severity in ChildrenSemantic proximity Read ↗

Interaction Between Genetic Susceptibility and COVID-19 Pathogenesis in Pediatric Multisystem Inflammatory Disorders: The Role of Immune Responses.Semantic proximity Read ↗

Host genetics of pediatric SARS-CoV-2 COVID-19 and multisystem inflammatory syndrome in childrenSemantic proximity Read ↗

The impact of genetic polymorphism on course and severity of the SARS-CoV-2 infection and COVID-19 disease.Semantic proximity Read ↗

The role of inflammatory gene polymorphisms in severe COVID-19: a review.Semantic proximity Read ↗

The seven enigmas of SARS-CoV-2: From the past to the futureSemantic proximity Read ↗

Genetics Insight for COVID-19 Susceptibility and Severity: A Review.Semantic proximity Read ↗

Exploring the interplay between host genetics and acute and long COVID: A narrative review.Semantic proximity Read ↗

The association of COVID-19 severity and susceptibility and genetic risk factors: A systematic review of the literature.Semantic proximity Read ↗

Genetic predisposition in patients with severe COVID-19.Semantic proximity Read ↗

Genetic polymorphisms associated with susceptibility to COVID-19 disease and severity: A systematic review and meta-analysis.Semantic proximity Read ↗

Human Genomics of COVID-19 Pneumonia: Contributions of Rare and Common VariantsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.