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Exploring the interplay between host genetics and acute and long COVID: A narrative review.

Clinics (Sao Paulo, Brazil) - 1 Jan 2025

Beuren Thais, Ferrari Filipe, Franzoni Leandro Tolfo, Goulart Cássia da Luz, Val Fernando, Cipriano Gerson, Stein Ricardo

Abstract excerpt

Over the past four years, pivotal discoveries have deepened the understanding of the relationship between genetic factors and SARS-CoV-2 infection. Numerous genes associated with severe COVID-19 suggest a potential genetic predisposition, which may help explain why some individuals develop more serious illnesses. Emerging evidence highlights the role of genes involved in pulmonary immunity, such as Forkhead box...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 40543387
DOI: 10.1016/j.clinsp.2025.100708
PMCID: PMC12216730

Genes

TMPRSS2
ACE
FOXP4
FYCO1
LZTFL1
MUC5B
SLC6A20
TYK2

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