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Multi-Trait Exome-Wide Association Study of Back Pain-Related Phenotypes.

Genes - 19 Oct 2023

Zorkoltseva Irina V, Elgaeva Elizaveta E, Belonogova Nadezhda M, Kirichenko Anatoliy V, Svishcheva Gulnara R, Freidin Maxim B, Williams Frances M K, Suri Pradeep, Tsepilov Yakov A, Axenovich Tatiana I

Abstract excerpt

Back pain (BP) is a major contributor to disability worldwide, with heritability estimated at 40-60%. However, less than half of the heritability is explained by common genetic variants identified by genome-wide association studies. More powerful methods and rare and ultra-rare variant analysis may offer additional insight. This study utilized exome sequencing data from the UK Biobank to perform a multi-trait...

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Identifiers

PMID: 37895311
DOI: 10.3390/genes14101962
PMCID: PMC10606006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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