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Article

Clinical Approaches for Mitochondrial Diseases.

Cells - 20 Oct 2023

Hong Seongho, Kim Sanghun, Kim Kyoungmi, Lee Hyunji

Abstract excerpt

Mitochondria are subcontractors dedicated to energy production within cells. In human mitochondria, almost all mitochondrial proteins originate from the nucleus, except for 13 subunit proteins that make up the crucial system required to perform 'oxidative phosphorylation (OX PHOS)', which are expressed by the mitochondria's self-contained DNA. Mitochondrial DNA (mtDNA) also encodes 2 rRNA and 22 tRNA species....

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PMID: 37887337
DOI: 10.3390/cells12202494
PMCID: PMC10605124

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