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Article

Experimental therapy for mitochondrial diseases.

Handbook of clinical neurology - 1 Jan 2023

Viscomi Carlo, Zeviani Massimo

Abstract excerpt

Mitochondrial diseases are extremely heterogeneous genetic disorders due to faulty oxidative phosphorylation (OxPhos). No cure is currently available for these conditions, beside supportive interventions aimed at relieving complications. Mitochondria are under a double genetic control carried out by the mitochondrial DNA (mtDNA) and by nuclear DNA. Thus, not surprisingly, mutations in either genome can cause...

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PMID: 36813318
DOI: 10.1016/B978-0-12-821751-1.00013-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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