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Article

The current landscape for the treatment of mitochondrial disorders.

Journal of genetics and genomics = Yi chuan xue bao - 20 Feb 2018

Slone Jesse, Gui Baoheng, Huang Taosheng

Abstract excerpt

The mitochondrial organelle is crucial to the energy metabolism of the eukaryotic cell. Defects in mitochondrial function lie at the core of a wide range of disorders, including both rare primary mitochondrial disorders and more common conditions such as Parkinson's disease and diabetes. Inherited defects in mitochondrial function can be found in both the nuclear genome and the mitochondrial genome, with the...

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PMID: 29502956
DOI: 10.1016/j.jgg.2017.11.008

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