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Article

wnt10a is required for zebrafish median fin fold maintenance and adult unpaired fin metamorphosis.

Developmental dynamics : an official publication of the American Association of Anatomists - 1 Jun 2024

Benard Erica L, Küçükaylak Ismail, Hatzold Julia, Berendes Kilian U W, Carney Thomas J, Beleggia Filippo, Hammerschmidt Matthias

Abstract excerpt

BACKGROUND: Mutations of human WNT10A are associated with odonto-ectodermal dysplasia syndromes. Here, we present analyses of wnt10a loss-of-function mutants in the zebrafish. RESULTS: wnt10a mutant zebrafish embryos display impaired tooth development and a collapsing median fin fold (MFF). Rescue experiments show that wnt10a is essential for MFF maintenance both during embryogenesis and later metamorphosis. The...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37870737
DOI: 10.1002/dvdy.672
PMCID: PMC11035493

Genes

MFF
WNT10A

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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