Article
FusionNeoAntigen: a resource of fusion gene-specific neoantigens.
Nucleic acids research - 5 Jan 2024
Kumar Himansu, Luo Ruihan, Wen Jianguo, Yang Chengyuan, Zhou Xiaobo, Kim Pora
Abstract excerpt
Among the diverse sources of neoantigens (i.e. single-nucleotide variants (SNVs), insertions or deletions (Indels) and fusion genes), fusion gene-derived neoantigens are generally more immunogenic, have multiple targets per mutation and are more widely distributed across various cancer types. Therefore, fusion gene-derived neoantigens are a potential source of highly immunogenic neoantigens and hold great promise...
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