Article
TP53 mutations predict for poor outcomes in patients with newly diagnosed aggressive B-cell lymphomas in the current era.
Blood advances - 12 Dec 2023
Landsburg Daniel J, Morrissette Jennifer Jd, Nasta Sunita D, Barta Stefan K, Schuster Stephen J, Svoboda Jakub, Chong Elise A, Bagg Adam
Abstract excerpt
Genetic subgroups of diffuse large B-cell lymphoma (DLBCL) have been identified through comprehensive genomic analysis; however, it is unclear whether this can be applied in clinical practice. We assessed whether mutations detected by clinical laboratory mutation analysis (CLMA) were predictive of outcomes in patients with newly diagnosed DLBCL/high-grade B-cell lymphoma (HGBL). Patients diagnosed from 2018 to...
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