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Novel insights on aquatic mammal MHC evolution: Evidence from manatee DQB diversity.

Developmental and comparative immunology - 1 Jul 2022

Sá André Luiz Alves de, Baker Pamela Ketrya Barreiros, Breaux Breanna, Oliveira Jairo Moura, Klautau Alex Garcia Cavalleiro de Macedo, Legatzki Kristian, Luna Fábia de Oliveira, Attademo Fernanda Löffler Niemeyer, Hunter Margaret Elizabeth, Criscitiello Michael Frederick, Schneider Maria Paula Cruz, Sena Leonardo Dos Santos

Abstract excerpt

The low diversity in marine mammal major histocompatibility complex (MHC) appears to support the hypothesis of reduced pathogen selective pressure in aquatic systems compared to terrestrial environments. However, the lack of characterization of the aquatic and evolutionarily distant Sirenia precludes drawing more generalized conclusions. Therefore, we aimed to characterize the MHC DQB diversity of two manatee...

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PMID: 35307479
DOI: 10.1016/j.dci.2022.104398

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