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Article

XRCC1 R194W and R399Q Polymorphisms and Colorectal Cancer Risk in a Northeastern Mexican Population.

Genetics research - 1 Jan 2023

Meza-Espinoza Juan Pablo, Peralta-Leal Valeria, Durán-González Jorge, Macías-Gómez Nelly, Bocanegra-Alonso Anabel, Leal-Ugarte Evelia

Abstract excerpt

Colorectal cancer (CRC) is one of the most common cancers worldwide. Its etiopathogenesis is complex, mainly influenced by genetic instability caused by the accumulation of mutations. The XRCC1 gene, which is involved in DNA repair, has been associated with CRC through the R194W (C194T) and R399Q (G399A) polymorphisms, but the results are inconsistent. Here, we analyzed the association of these polymorphisms with...

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Identifiers

PMID: 37829155
DOI: 10.1155/2023/5565646
PMCID: PMC10567464

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