Article
A meta-analysis on XRCC1 and XRCC3 polymorphisms and colorectal cancer risk.
International journal of colorectal disease - 1 Feb 2010
Jiang Zheng, Li Chunxiang, Xu Ye, Cai Sanjun
Abstract excerpt
PURPOSE: Studies on polymorphism of X-ray repair cross-complementing group 1 (XRCC1), group 3 (XRCC3), and colorectal cancer risk are inconclusive. The purpose of this study is to evaluate the role of XRCC1 R399Q, R194W, and XRCC3 T241M genotypes in colorectal cancer susceptibility. METHODS: We performed a meta-analysis on all available studies that provided 3,514/4,686 cases/controls for R399Q, 2,767/3,907...
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