A meta-analysis on XRCC1 and XRCC3 polymorphisms and colorectal cancer risk.

doi:10.1007/s00384-009-0817-9

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Article

A meta-analysis on XRCC1 and XRCC3 polymorphisms and colorectal cancer risk.

International journal of colorectal disease - 1 Feb 2010

Jiang Zheng, Li Chunxiang, Xu Ye, Cai Sanjun

Abstract excerpt

PURPOSE: Studies on polymorphism of X-ray repair cross-complementing group 1 (XRCC1), group 3 (XRCC3), and colorectal cancer risk are inconclusive. The purpose of this study is to evaluate the role of XRCC1 R399Q, R194W, and XRCC3 T241M genotypes in colorectal cancer susceptibility. METHODS: We performed a meta-analysis on all available studies that provided 3,514/4,686 cases/controls for R399Q, 2,767/3,907...

Topics

Aged
Cluster Analysis
Colorectal Neoplasms
DNA-Binding Proteins
Female
Gene Expression Regulation, Neoplastic
Gene Frequency
Genetic Predisposition to Disease
Humans
Linear Models
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Middle Aged

Odds Ratio

Polymorphism, Genetic

Publication Bias

Risk Assessment

Risk Factors

X-ray Repair Cross Complementing Protein 1

Source

Open in PubMed

Identifiers

PMID: 19915856
DOI: 10.1007/s00384-009-0817-9

Genes

XRCC1
XRCC3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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