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Article

Impaired mitophagosome–lysosome fusion mediates olanzapine‐induced aging

13 Oct 2023

Abstract excerpt

The lifespan of schizophrenia patients is significantly shorter than the general population. Olanzapine is one of the most commonly used antipsychotic drugs (APDs) for treating patients with psychosis, including schizophrenia and bipolar disorder. Despite their effectiveness in treating positive and negative symptoms, prolonged exposure to APDs may lead to accelerated aging and cognitive decline, among other side...

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PMID: 37828862
DOI: 10.1111/acel.14003

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