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Impaired Mitophagy in Neurons and Glial Cells during Aging and Age-Related Disorders

23 Sept 2021

Abstract excerpt

Aging is associated with a decline in cognitive function, which can partly be explained by the accumulation of damage to the brain cells over time. Neurons and glia undergo morphological and ultrastructure changes during aging. Over the past several years, it has become evident that at the cellular level, various hallmarks of an aging brain are closely related to mitophagy. The importance of mitochondria quality...

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PMID: 34638589
DOI: 10.3390/ijms221910251

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