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Article

Urolithin A prevents age-related hearing loss in C57BL/6J mice likely by inducing mitophagy

24 Sept 2024

Abstract excerpt

Mitochondrial dysfunction with aging is associated with the development of age-related hearing loss. Mitophagy is a cardinal mechanism to maintain a healthy mitochondrial population through the turnover of damaged mitochondria. Declining mitophagy with age causes a buildup of damaged mitochondria, leading to sensory organ dysfunction. The effect of Urolithin A (UA), a mitophagy inducer, was investigated on...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 39307249
DOI: 10.1016/j.exger.2024.112589

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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