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Article

Cannabidiol induces autophagy and improves neuronal health associated with SIRT1 mediated longevity

20 Apr 2022

Abstract excerpt

Autophagy is a catabolic process to eliminate defective cellular molecules via lysosome-mediated degradation. Dysfunctional autophagy is associated with accelerated aging, whereas stimulation of autophagy could have potent anti-aging effects. We report that cannabidiol (CBD), a natural compound from Cannabis sativa, extends lifespan and rescues age-associated physiological declines in C. elegans. CBD promoted...

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PMID: 35445360
DOI: 10.1007/s11357-022-00559-7

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