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Article

Association of Blood-Based DNA Methylation Markers With Late-Onset Alzheimer Disease: A Potential Diagnostic Approach.

Neurology - 4 Dec 2023

Acha Blanca, Corroza Jon, Sánchez-Ruiz de Gordoa Javier, Cabello Carolina, Robles Maitane, Méndez-López Iván, Macías Mónica, Zueco Sara, Roldan Miren, Urdánoz-Casado Amaya, Jericó Ivonne, Erro Maria Elena, Alcolea Daniel, Lleo Alberto, Blanco-Luquin Idoia, Mendioroz Maite

Abstract excerpt

BACKGROUND AND OBJECTIVES: There is an urgent need to identify novel noninvasive biomarkers for Alzheimer disease (AD) diagnosis. Recent advances in blood-based measurements of phosphorylated tau (pTau) species are promising but still insufficient to address clinical needs. Epigenetics has been shown to be helpful to better understand AD pathogenesis. Epigenetic biomarkers have been successfully implemented in...

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Identifiers

PMID: 37827850
DOI: 10.1212/WNL.0000000000207865
PMCID: PMC10752644

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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