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Article

FCRL2 expression predicts IGHV mutation status and clinical progression in chronic lymphocytic leukemia.

Blood - 1 Jul 2008

Li Fu Jun, Ding Shouluan, Pan Jicun, Shakhmatov Mikhail A, Kashentseva Elena, Wu Jiongru, Li Yufeng, Soong Seng-jaw, Chiorazzi Nicholas, Davis Randall S

Abstract excerpt

CD38 and ZAP-70 are both useful prognostic markers for B-cell chronic lymphocytic leukemia (CLL), but are variably discordant with IGHV mutation status. A total of 5 human Fc receptor-like molecules (FCRL1-5) have tyrosine-based immunoregulatory potential and are expressed by B-lineage subpopulations. To determine their prognostic potential in CLL, FCRL expression was compared with IGHV mutation status, CD38 and...

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Topics

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Share to ADP-ribosyl Cyclase 1
Share to B-Lymphocytes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, Immunoglobulin Heavy Chain

Share to Leukemia, Lymphocytic, Chronic, B-Cell

Share to Receptors, Cell Surface

Share to Receptors, Fc

Share to Receptors, Immunologic

Share to ZAP-70 Protein-Tyrosine Kinase

Source

Open in PubMed Open full text

Identifiers

PMID: 18314442
DOI: 10.1182/blood-2008-01-131359
PMCID: PMC2435687

Genes

FCRL2
FCRL1
FCRL3
FCRL5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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FCRL2 expression predicts IGHV mutation status and clinical progression in chronic lymphocytic leukemia.PMID 18314442Read ↗

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