Article
Growing and dividing: how O-GlcNAcylation leads the way.
The Journal of biological chemistry - 1 Nov 2023
Saunders Harmony, Dias Wagner B, Slawson Chad
Abstract excerpt
Cell cycle errors can lead to mutations, chromosomal instability, or death; thus, the precise control of cell cycle progression is essential for viability. The nutrient-sensing posttranslational modification, O-GlcNAc, regulates the cell cycle allowing one central control point directing progression of the cell cycle. O-GlcNAc is a single N-acetylglucosamine sugar modification to intracellular proteins that is...
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