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Growth differentiation factor 7 autocrine signaling promotes hepatic progenitor cell expansion in liver fibrosis

5 Oct 2023

Abstract excerpt

BACKGROUND AND AIM: Liver fibrosis is prevalent among chronic diseases of the liver and represents a major health burden worldwide. Growth differentiation factor 7 (GDF7), a member of the TGFβ protein superfamily, has been recently investigated for its role in repair of injured organs, but its role in chronic liver diseases remains unclear. Here, we examined hepatic GDF7 expression and its association with...

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PMID: 37798809
DOI: 10.1186/s13287-023-03493-3

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