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Metabolite profiles and DNA methylation in metabolic syndrome: a two-sample, bidirectional Mendelian randomization

15 Sept 2023

Abstract excerpt

Introduction: Metabolic syndrome (MetS) increases the risk of cardiovascular disease and death. Previous ‘-omics’ studies have identified dysregulated serum metabolites and aberrant DNA methylation in the setting of MetS. However, the relationship between the metabolome and epigenome have not been elucidated. In this study, we identified serum metabolites associated with MetS and DNA methylation, and we conducted...

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Identifiers

PMID: 37779905
DOI: 10.3389/fgene.2023.1184661

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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