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Genome-wide search identified DNA methylation sites that regulate the metabolome

18 May 2023

Abstract excerpt

Background: Identifying DNA methylation sites that regulate the metabolome is important for several purposes. In this study, publicly available GWAS data were integrated to find methylation sites that impact metabolome through a discovery and replication scheme and by using Mendelian randomization. Results: The outcome of analyses revealed 107 methylation sites associated with 84 metabolites at the genome-wide...

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PMID: 37274792
DOI: 10.3389/fgene.2023.1093882

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