Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Multi-stage metabolomics and genetic analyses identified metabolite biomarkers of metabolic syndrome and their genetic determinants.

EBioMedicine - 1 Dec 2021

Wu Qiong, Li Jiankang, Sun Xiaohui, He Di, Cheng Zongxue, Li Jun, Zhang Xuhui, Xie Yongming, Zhu Yimin, Lai Maode

Abstract excerpt

BACKGROUND: Metabolic syndrome (MetS) is a cluster of multiple cardiometabolic risk factors that increase the risk of type 2 diabetes and cardiovascular diseases. Identifying novel biomarkers of MetS and their genetic associations could provide insights into the mechanisms of cardiometabolic diseases. METHODS: Potential MetS-associated metabolites were screened and internally validated by untargeted metabolomics...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to Early Diagnosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome-Wide Association Study

Share to Linear Models

Share to Mendelian Randomization Analysis

Share to Metabolic Syndrome

Share to Metabolomics

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 34801968
DOI: 10.1016/j.ebiom.2021.103707
PMCID: PMC8605407

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Multi-stage metabolomics and genetic analyses identified metabolite biomarkers of metabolic syndrome and their genetic determinants.PMID 34801968Read ↗

Metabolomics and nutrient intake reveal metabolite–nutrient interactions in metabolic syndrome: insights from the Korean Genome and Epidemiology StudySemantic proximity Read ↗

Integrative metabolomics and genomics reveal molecular signatures for type 2 diabetes and its cardiovascular complications.Semantic proximity Read ↗

How to Screen and Prevent Metabolic Syndrome in Patients of PCOS Early: Implications From MetabolomicsSemantic proximity Read ↗

Metabolomic epidemiology offers insights into disease aetiology.Semantic proximity Read ↗

Comprehensive Analysis of Serum Metabolites and Whole Blood Cell Transcriptome reveals the Dysregulated Metabolic Pathways in Metabolically Healthy Obesity.Semantic proximity Read ↗

Multi-omics profiling: the way toward precision medicine in metabolic diseasesSemantic proximity Read ↗

The Metabolic Syndrome in Men study: a resource for studies of metabolic and cardiovascular diseases.Semantic proximity Read ↗

Power of metabolomics in biomarker discovery and mining mechanisms of obesity.Semantic proximity Read ↗

Advances in Metabolomics: A Comprehensive Review of Type 2 Diabetes and Cardiovascular Disease InteractionsSemantic proximity Read ↗

Metabolomic and Lipidomic Signatures of Metabolic Syndrome and its Physiological Components in Adults: A Systematic Review.Semantic proximity Read ↗

Metabolite profiles and DNA methylation in metabolic syndrome: a two-sample, bidirectional Mendelian randomizationSemantic proximity Read ↗

Metabolome‐Genome‐Wide Association Study (mGWAS) Reveals Novel Metabolites Associated with Future Type 2 Diabetes Risk and Susceptibility Loci in a Case‐Control Study in a Chinese Prospective CohortSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.