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Article

Application of real-time PCR-based multicolor melting curve with automatic analysis system in pregestational and prenatal thalassemia diagnoses.

Annals of human genetics - 1 Nov 2023

Tang Xue-Wei, Jiang Fan, Li Jian, Lin Xiao-Mei, Zhou Jian-Ying, Wan Jun-Hui, Zuo Lian-Dong, Qu Yan-Xia, Li Fa-Tao, Chen Gui-Lan, Li Dong-Zhi

Abstract excerpt

BACKGROUND: To evaluate the value of the real-time PCR-based multicolor melting curve analysis (MMCA) with an automatic analysis system used in a mass thalassemia screening and prenatal diagnosis program. METHODS: A total of 18,912 peripheral blood samples from 9456 couples and 1150 prenatal samples were detected by MMCA assay. All prenatal samples were also tested by a conventional method. Samples with unknown...

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PMID: 37771257
DOI: 10.1111/ahg.12531

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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