Article
Rapid diagnosis of alpha-thalassemia by melting curve analysis.
The Journal of molecular diagnostics : JMD - 1 May 2010
Munkongdee Thongperm, Vattanaviboon Phantip, Thummarati Parichut, Sewamart Paijit, Winichagoon Pranee, Fucharoen Suthat, Svasti Saovaros
Abstract excerpt
alpha-Thalassemia is an inherited hemoglobin disorder that results from defective synthesis of alpha-globin protein. Couples who both carry the alpha-thalassemia-1 gene are at risk of having a fetus with Hb Bart's hydrops fetalis. Rapid and accurate screening for individuals carrying the alpha-thalassemia-1 gene is the most effective strategy to prevent and control this severe form of thalassemia. In this study,...
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