Article
Antioxidant Behavioural Phenotype in the Immp2l Gene Knock-Out Mouse.
Genes - 28 Aug 2023
Lawther Adam J, Zieba Jerzy, Fang Zhiming, Furlong Teri M, Conn Illya, Govindaraju Hemna, Choong Laura L Y, Turner Nigel, Siddiqui Khawar Sohail, Bridge Wallace, Merlin Sam, Hyams Tzipi Cohen, Killingsworth Murray, Eapen Valsamma, Clarke Raymond A, Walker Adam K
Abstract excerpt
Mitochondrial dysfunction is strongly associated with autism spectrum disorder (ASD) and the Inner mitochondrial membrane protein 2-like (IMMP2L) gene is linked to autism inheritance. However, the biological basis of this linkage is unknown notwithstanding independent reports of oxidative stress in association with both IMMP2L and ASD. To better understand IMMP2L's association with behaviour, we developed the...
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