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Article

Bladder dysfunction in a new mutant mouse model with increased superoxide--lack of nitric oxide?

The Journal of urology - 1 Feb 2010

Soler Roberto, Füllhase Claudius, Lu Baisong, Bishop Colin E, Andersson Karl-Erik

Abstract excerpt

PURPOSE: Nitric oxide mediates urethral smooth muscle relaxation and may also be involved in detrusor activity control. Mice with mutation in the Immp2l gene have high superoxide ion levels and a consequent decrease in the bioavailable amount of nitric oxide. We studied bladder function in this mouse model. MATERIAL AND METHODS: Young male mutants at ages 4 to 6 months, old female mutants at age 18 months and...

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Identifiers

PMID: 20022053
DOI: 10.1016/j.juro.2009.09.074
PMCID: PMC3772662

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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