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Article

The Genetic Architecture of Congenital Diarrhea and Enteropathy

3 Apr 2025

Abstract excerpt

Background Next-generation sequencing has enabled precision therapeutic approaches that have improved the lives of children with rare diseases. Congenital diarrhea and enteropathies (CODEs) are associated with high morbidity and mortality. Although treatment of these disorders is largely supportive, emerging targeted therapies based on genetic diagnoses include specific diets, pharmacologic treatments, and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 40174224
DOI: 10.1056/nejmoa2405333

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