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Article

Characterization of mismatch‐repair/microsatellite instability‐discordant endometrial cancers

26 Sept 2023

Abstract excerpt

BACKGROUND: Mismatch-repair (MMR)/microsatellite instability (MSI) status has therapeutic implications in endometrial cancer (EC). The authors evaluated the concordance of testing and factors contributing to MMR expression heterogeneity. METHODS: Six hundred sixty-six ECs were characterized using immunohistochemistry (IHC), MSI testing, and mut-L homolog 1 (MLH1) methylation. Select samples underwent...

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PMID: 37751191
DOI: 10.1002/cncr.35030

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