Article
Exploring the Causality Between Plasma Brain-Derived Neurotrophic Factor and Neurological Diseases: A Mendelian Randomization Study.
Journal of Alzheimer's disease : JAD - 1 Jan 2023
Chen Shihao, Huang Wenting, He Tao, Zhang Mulan, Jin Xing, Jiang Lelin, Xu Huiqin, Chen Keyang
Abstract excerpt
BACKGROUND: Brain-derived neurotrophic factor (BDNF) is a protein synthesized in the brain and widely expressed in the nervous system. Previous studies have demonstrated a controversial role of BDNF in neurological diseases. OBJECTIVE: In this study, we aimed to assess the association between BDNF levels and the risk of neurological diseases by Mendelian randomization analysis. METHODS: From a genome-wide...
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