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Article

The associations between plasma soluble Trem1 and neurological diseases: a Mendelian randomization study.

Journal of neuroinflammation - 6 Sept 2022

Shi Xiaolei, Wei Tao, Hu Yachun, Wang Meng, Tang Yi

Abstract excerpt

BACKGROUND: Triggering receptor expressed on myeloid cell 1 (Trem1) is an important regulator of cellular inflammatory responses. Neuroinflammation is a common thread across various neurological diseases. Soluble Trem1 (sTrem1) in plasma is associated with the development of central nervous system disorders. However, the extent of any causative effects of plasma sTrem1 on the risk of these disorders is still...

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Identifiers

PMID: 36068612
DOI: 10.1186/s12974-022-02582-z
PMCID: PMC9446564

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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