Article
Genetic mutation signature for relapse prediction in normal karyotype acute myeloid leukemia.
Experimental hematology - 1 Dec 2023
Han Lijie, Wu Jiaying, Lyu Xiaodong, Yu Jifeng, Han Xiaolin, Zhao Hongmian, Bian Zhilei, Li Wei, Fan Wenjuan, He Chen, Wang Weimin, Zhang Mengmeng, Li Yafei, Liu Chao, Sun Hui, Cao Haixia, Sang Li'na, Zhang Jun, Jiang Zhongxing, Peng Jie
Abstract excerpt
Risk stratification for normal karyotype acute myeloid leukemia (NK-AML) remains unsatisfactory, which is reflected by the high incidence of leukemia relapse. This study aimed to evaluate the role of gene mutations and clinical characterization in predicting the relapse of patients with NK-AML. A prognostic system for NK-AML was constructed. A panel of gene mutations was explored using next-generation sequencing....
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