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Gene expression signature predicts relapse in adult patients with cytogenetically normal acute myeloid leukemia

8 Mar 2021

Abstract excerpt

Although ∼80% of adult patients with cytogenetically normal acute myeloid leukemia (CN-AML) achieve a complete remission (CR), more than half of them relapse. Better identification of patients who are likely to relapse can help to inform clinical decisions. We performed RNA sequencing on pretreatment samples from 268 adults with de novo CN-AML who were younger than 60 years of age and achieved a CR after...

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PMID: 33683341
DOI: 10.1182/bloodadvances.2020003727

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