Article
[Study of the resistance of Candida guilliermondii to polyene antibiotics].
Mikrobiologiia - 1 Jan 2000
Durasova E N, Mikhaĭlova N P, V'iunova K A, Bakulev V M, Sokolov V N
Abstract excerpt
250 Candida guilliermondii strains resistant to the polyene antibiotics nystatin, levorin and amphotericin B were obtained using UV irradiation. When the mutant strains became resistant to one of the polyene antibiotics, their resistance to the other ones changed. Phenotypic analysis showed that the resistance of the strains to polyene antibiotics did not make them susceptible to a rise in osmotic pressure and to...
Topics
- Antifungal Agents
- Candida
- Drug Resistance, Microbial
- Phenotype
- Polyenes