Article
[The effect of oxygen deficiency on the stability of the yeast Saccharomyces cerevisiae to the polyenic antibiotic nystatin].
Mikrobiologiia - 1 Jan 2000
Ekhvalova T V, Mikhaĭlova N P, Ogorodnikova T E, V'iunov K A
Abstract excerpt
Oxygen deficiency was shown to affect the resistance of different Saccharomyces cerevisiae strains to nystatin, a polyenic antibiotic. This resistance decreased upon oxygen deficiency in the wild-type strains alpha'1 and 7A-P192 as well as in the mutant strains NYS 2, NYS 3 and NYS 4, but remained unchanged in the mutants NYS-1 and NYS 5. The qualitative composition of sterols was studied in the strains with a...
Topics
- Cell Hypoxia
- Drug Resistance, Microbial
- Ergosterol
- Genes, Fungal
- Mutation
- Nystatin
- Saccharomyces cerevisiae