Article
Change of cell wall chitin content in amphotericin B resistant Kluyveromyces strains.
FEMS microbiology letters - 29 Oct 2002
Bahmed Karim, Bonaly Roger, Wathier Michel, Pucci Bernard, Coulon Joël
Abstract excerpt
The culture of two Kluyveromyces species, Kluyveromyces lactis (ATCC 96897) and Kluyveromyces bulgaricus (ATCC 96631), in the presence of subinhibitory doses of amphotericin B leads to the selection of mutants which are resistant to this polyene. The mutants show an alteration of their cell wall composition with the main change corresponding to an increase of chitin. The enzyme activities involved in the...
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